"Aquapura Douro Valley hotel is located across the river from Régua, featuring an 18th-century quinta redesigned in a faintly Asiatic style. The hotel offers floor-to-ceiling windows in the guest rooms with views of vineyards or the Douro River, a spa with Asian-inspired treatments like Thai massages and bamboo shoot facial masks, and a restaurant with inventive cuisine by chef Emmanuel Soares." - Ray Isle