21c Museum Hotel Lexington

Hotel · Lexington

21c Museum Hotel Lexington

Hotel · Lexington

8

167 W Main St, Lexington, KY 40507

Photos

21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by Courtesy 21c Museum Hotels/Photo by Magnus Lindqvist
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null
21c Museum Hotel Lexington by null

Highlights

Nestled in a revitalized historic bank building, the 21c Museum Hotel offers chic rooms adorned with contemporary art, a lively restaurant, and convenient access to downtown Lexington's vibrant scene.  

Featured in Conde Nast Traveler
Featured in Afar

167 W Main St, Lexington, KY 40507 Get directions

21cmuseumhotels.com
@21clex

$$$

Information

Static Map

167 W Main St, Lexington, KY 40507 Get directions

+1 859 899 6800
21cmuseumhotels.com
@21clex

$$$

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Last updated

Jul 27, 2025

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@cntraveler

21c Museum Hotel, Lexington

"How did it strike you on arrival?In absolute shock that this art museum-hotel combo is in Kentucky, you're met with an incredibly ornate lobby and the most fabulous front desk. The 21c Museum Hotel Lexington is the embodiment of the boutique property. There's a million different directions that your eye can wander to, with a plethora of art throughout the hotel. Nice. What’s the crowd like?You've really got to love and appreciate art and design to stay here. It's in your face at all times. The crowd is posh, and you better believe they're Instagramming every nook and cranny of the place. How was check in?There were zero difficulties with check-in. I was too smitten with the decor to even notice otherwise. The good stuff: Tell us about your room.I was surprised that the room, a corner king, was as comfortable and plush as it was. Muted walls and carpet made the apple-green sofa pop. Each room is adorned with original artwork that's well-lit with natural sunlight. The bathroom does the job, but you won't be dropping your jaw over it. How about the little things, like mini bar, or shower goodies. Any of that find its way into your suitcase?Malin+Goetz bath products and Nespresso coffee machines are it, as far as in-room amenities go. Room service and food: Worth it?Lockbox is the restaurant in the hotel and it doesn't disappoint. Order like a local, and enjoy a bourbon before you dive into their country ham hushpuppies or seed-crusted catfish. The vibe of the place permits a LBD or dinner jacket, but doesn't frown on casual, either. Anything stand out about other services and features? Whether it’s childcare, gyms, spas, even parking—whatever stuck with you.Absolutely smitten with the hotel's gift shop. Pick up something special for the design-minded friend in your life. Bottom line: worth it, and why?Absolutely! If you're looking for a little stay with your art, the 21c Museum Hotel is your ticket. One of the strongest dinning options in town is just downstairs from your room."

https://www.cntraveler.com/hotels/lexington/21c-museum-hotel-lexington
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@onthegrid

On the Grid : Modern Motel

"This mansion was built in 1885, and since then it’s seen many uses. Now, it’s a motel and art studio space. Local artists rent rooms to work on their stuff, and discerning travelers rent rooms to explore Lexington in a centrally located, decked out living space. Keep an eye out for Colonel Sanders." - Bullhorn

https://onthegrid.city/lexington/lexington-ky/modern-motel
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@onthegrid

On the Grid : 21c Museum Hotel

"The historic converges with modern at 21c Lexington. The boutique hotel and museum is located in the 100-year-old First National Bank Building on Main Street and exhibits a rotating and permanent collection of contemporary art. You don’t have to stay here to experience modern art in downtown Lexington, the museum experience is free and open to the public. Get a leg up on the next day’s forecast while you dine at the hotel’s restaurant, Lockbox – a Biegert & Bergström art installation changes color depending on the tomorrow’s weather." - Bullhorn

https://onthegrid.city/lexington/lexington-ky/21c-museum-hotel
View Postcard for 21c Museum Hotel Lexington
@onthegrid

"21c Museum Hotel, Lexington Ky by Bullhorn. The historic converges with modern at 21c Lexington. The boutique hotel and museum is located in the 100-year-old First National Bank Building on Main Street and exhibits a rotating and permanent collection of contemporary art. You don’t have to stay here to experience modern art in downtown Lexington, the museum experience is free and open to the public. Get a leg up on the next day’s forecast while you dine at the hotel’s restaurant, Lockbox – a Biegert & Bergström art installation changes color depending on the tomorrow’s weather."

Lexington, Kentucky, USA
View Postcard for 21c Museum Hotel Lexington
@onthegrid

"21c Museum Hotel, Lexington Ky by Bullhorn. The historic converges with modern at 21c Lexington. The boutique hotel and museum is located in the 100-year-old First National Bank Building on Main Street and exhibits a rotating and permanent collection of contemporary art. You don’t have to stay here to experience modern art in downtown Lexington, the museum experience is free and open to the public. Get a leg up on the next day’s forecast while you dine at the hotel’s restaurant, Lockbox – a Biegert & Bergström art installation changes color depending on the tomorrow’s weather."

Lexington, Kentucky, USA
View Postcard for 21c Museum Hotel Lexington