Emily I.
Yelp
This hotel is truly the definition of luxury. Beautifully decorated with white marble covering the entry way, floors, and most of the lobby.
The staff puts the guests first and strives to meet any and all needs you may have. My husband had requested a (surprise for me) special treat for our anniversary, and the hotel staff provided decadent treats (wish I took a photo, but ate them too fast) and a bottle of red wine. The concierge also helped us secure tickets to the Borghese Gallery with only 24 hours notice!
Amenities include a spa that features a Turkish bath, sauna, and whirlpool. It's like your own little escape after a long day of walking around Rome.
The Aleph Rome hotel is a very short walk from the Barberini metro stop on the A line. Could be slightly difficult with a lot of luggage (slightly uphill and uneven sidewalks), but very convenient for getting around to local sites.
Breakfast was included for us (we have status with Hilton), but it's definitely worth paying for (if needed). There is a menu to order from (eggs benedict, crepes, omelets, etc), as well as a buffet of meats, cheeses, breads, pastries, fresh fruit, and juices.
If you are from the US, or only speak English, you will have no issues here. All of the staff speaks excellent English and we experienced no confusion or difficulty communicating whatsoever.