Farmacia dei Sani

Restaurant · Ruffano

Farmacia dei Sani

Restaurant · Ruffano

2

Piazza del Popolo, 14, 73049 Ruffano LE, Italy

Photos

Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null
Farmacia dei Sani by null

Highlights

Farmacia Dei Sani crafts modern Puglian cuisine with inventive flavors in a charming historic Ruffano piazza, served with friendly, relaxed vibes.  

Yelp Rating
4.5
Featured on Michelin
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Piazza del Popolo, 14, 73049 Ruffano LE, Italy Get directions

farmaciadeisani.eu
@farmacia_dei_sani

$$ · Menu

Reserve

Information

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Piazza del Popolo, 14, 73049 Ruffano LE, Italy Get directions

+39 339 833 2514
farmaciadeisani.eu
@farmacia_dei_sani

$$ · Menu

Reserve

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Last updated

Jul 30, 2025

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@michelinguide

Farmacia dei Sani

"Occupying a corner of the central Piazza del Popolo in the delightful historic centre of Ruffano, this family restaurant (also a liqueur-maker) is surrounded by old palazzi which add to the charm of its setting. The Puglian cuisine served here has a modern twist while remaining unfussy in style and firmly anchored in the region. The service is quick, and each guest is greeted with a smile by the Rizzo family." - Michelin Inspector

https://guide.michelin.com/en/puglia/ruffano/restaurant/farmacia-dei-sani
View Postcard for Farmacia dei Sani
@katieparla

The innovative dishes at this restaurant deep in Salento’s interior are inspired by the region’s ingredients, which are elevated using modern techniques and outside-the-box flavor contrasts.

Puglia
View Postcard for Farmacia dei Sani

Oscar Vadillo

Google
Such a good place. Each plate pushes things a little bit further in a great way. Pork Belly + Cod, just spectacular. On top of that, the vibe is truly relaxing for a perfect evening. Staff very helpful and kind. So in few words, I would truly recommend it 👌

Nick Peak

Google
A fantastic dining experience. Two must-have items: the egg starter and the signature pistachio/lemon spaghetti It’s an excellent dining experience, even if some of the courses were less than spectacular.

Marco M.

Google
Amazing evening with delicious food and very friendly and kind service. Any time again. Thanks

Rocco Santoro

Google
What a great restaurant! A true gem in the heart of Salento! A great tasting menu, professional and friendly service, delicious food and a selection of wines that is not so easy to find around in the area! I’ll definitely be back soon!

Jay Stewart

Google
My partner suggested that we recommend Farmacia Dei Sani for my friends visiting from Long Beach, CA and we were not disappointed. We made reservations the night before and we were lucky to have a table at the desired time. When we arrived, we were greeted by a friendly host and seated. They answered our questions about the menu and took care of us throughout the time we were there. The food was exquisite in both presentation and taste. I highly recommend Farmacia Dei Sani.

Chris G

Google
The food is excelent, you can’t complain at all. The staff is really nice and helpful. The location is interesting, much nicer at night with the lights on, but there’s not much to complain about.

Luciana Naccari

Google
Lovely atmosphere chic but relaxed at the same time. The food is amazing with a great balance of crispy, creamy and callous. Rich flavours crowned by local wines.

Steven Leach

Google
Delicious, rich, complex tastes. A lovely meal, fantastic service, a pleasantly surprising restaurant - I look forward to dining here again.