"When it was founded in 1852 in St. Louis’s Soulard neighborhood, the Anheuser-Busch Brewery was revered for its access to the Mississippi River and natural caves that were used to keep beer cold prior to modern refrigeration. Today, it sprawls across 1,655,280 square feet of building space, set on a 142-acre site. Tours here range from free 45-minute experiences to food-pairing sessions and even make-your-own beer classes. There’s also an on-site beer garden for social sipping. Perhaps the best attraction, however, is the brewery’s Clydesdale horses—book the Horses & Heritage Tour for a behind-the-scenes look at their lives, plus the chance to pet and pose for pictures with the stunning creatures."