"One of California's 14 Cultural Districts, this historic, artsy neighborhood is rooted in Mexican and Chicano cultures. The most obvious proof is Chicano Park, the neighborhood's collection of more than 80 outdoor murals painted onto the concrete girders of the Coronado Bridge. The larger-than-life portraits depict iconic cultural figures, like revolutionary Emiliano Zapata and Aztec goddesses. Many of the hip, modern businesses that have landed are still rooted in the community's culture. There's Por Vida for coffee, Border X Brewing for Mexican-inspired craft beers like a horchata brew, Salud! for street tacos that garners long (long) lines, and Simón Limón, which sells beauty and home goods. And for old-school flavor and some of the best Mexican food in San Diego, don't miss a meal at Las Cuatro Milpas, but get there early—they usually sell out by lunchtime." - Marie Tutko, Archana Ram