"It’s impossible to say which shop has the best po’ boys, but this Uptown contender is always in the running. Domilise’s doesn’t look like much from the outside, a nondescript corner shop identified only with a hand-printed sign for decades. Inside, longtime employees sling giant versions of the iconic sandwiches to locals, politicians, visiting celebrities, and anyone with good taste. The po’ boys might be considered pricey (a large shrimp goes for about $16), but they’re generous and worth every penny, especially the melt in your mouth roast beef and crispy fried shrimp. Always say yes to the sandwich fully dressed, topped with shredded lettuce, tomatoes, pickles, and mayonnaise." - Beth D’Addono