"Of all the burgers on the list, Sam’s is likely to be held closest to San Franciscans’ hearts. Sam’s first opened its doors in 1966 and has been serving comfort food — until the wee morning hours — ever since. This no-frills burger stars a chuck blend with cheese, lettuce, and tomato on a sesame bun. These days they’re flipping patties right off Columbus Avenue until midnight seven days a week." - Lauren Saria, Eater Staff, Paolo Bicchieri