Awasi Patagonia

"We all dream of dropping off the map. Here’s a place you can actually do that: the wonderfully isolated region of Patagonia. Awasi is the southernmost Relais & Chateaux in the world. The main attraction is the setting itself, and the 14 private villas are located between the Torres del Paine Mountain Range, the Patagonian Steppe, and Lake Sarmiento (all littered with guanacos, puma, and condors). The minimal footprint of the hotel on the grounds makes it all the more epic. Take your own private guide and 4WD vehicle for some serious exploration. Then head back for a raging fire and hot tub." (Starting $4,400/night)