"Located in a Renaissance-era palace once owned by the Medici family, Locale is fine dining for craft-cocktail enthusiasts, delivering stellar service under original frescos. The avant-garde cocktail lounge (which won a spot on the World’s 50 Best Bars list in 2022) boasts towering shelves of specialty spirits and an undercurrent of experimental flair. Along with the drinks, emerging young chef Simone Caponnetto prepares an inventive modernist tasting menu with hedonistic tendencies, such as pork liver crepinette (sausage), stuffed squid in Champagne, and parcels of pine nut milk burrata. There are also exquisite bar bites like skirt steak with salsa verde, sweet Tuscan friggitelli peppers, or goat cheese truffle fondue croquettes. Know before you go: Below the main space, there’s an underground science lab, where bartenders concoct artichoke-infused sodas and redistilled gins for herbaceous Americanos and Negronis, house-made kombucha with locally grown saffron, and CBD-vaporized cocktails." - Coral Sisk