"Located in a Renaissance-era palace once owned by the Medici family, Locale is fine dining for craft-cocktail enthusiasts, with stellar service under original frescos. The avant-garde cocktail lounge (which won a spot on the World’s 50 Best Bars list in 2022) boasts towering shelves of specialty spirits and an undercurrent of experimental flair. Along with the drinks, emerging young chef Simone Caponnetto prepares an inventive modernist seasonal tasting menu that features items like wild Tuscan herbs paired with smoked teas, chard millefoglie, and savory gelato; the kitchen also hosts occasional pop-ups by Italian chefs of similar vision. Below the main space, there’s an underground science lab, where bartenders concoct carrot-infused vodkas, redistilled gins, house-made kombucha with obscure local dried flowers, and CBD-vaporized cocktails." - Coral Sisk