Our Readers' Favorite Cities in Central and South America in 2022

"Recommended by a reader as a place to stay in Cartagena's Old Town, this small, 32-room property is well situated for exploring the city's UNESCO-protected historic center and its ancient churches." - Samantha Falewée Samantha Falewée Samantha Falewée is an associate editor for Travel + Leisure, interested in adventure and culinary travel, Indigenous culture, and wildlife conservation. A France-U.S. citizen, she speaks French and is a certified wine nerd by the Wine & Spirit Education Trust (Level II). Travel + Leisure Editorial Guidelines